Description
Shortly about Testolone
- Effectively increases muscle mass, strength indicators and gives athletes a relief and powerful appearance and pronounced venousness. Athletes experience greater fullness and stiffness during the intake.
- Suppresses own testosterone significantly compared to lighter compounds such as Ostarine and Andarine
- It has a protective effect on the prostate gland, therefore it is useful when used together with anabolic steroids.
- Proven positive effect on breast cancer reduction
What is Testolone
RAD140 is a new substance that is still being studied in pharmaceutical trials. RAD140 was developed by Radius Pharmaceuticals in the late 2000s as a potential therapeutic agent to prevent muscle wasting in terminally ill patients. It is currently being investigated as a therapeutic agent for breast cancer patients. RAD140 has excellent pharmacokinetic properties and is powerful anabolic. It has similar anabolic effects to LGD4033 and also appears to be a partial agonist in prostate tissue. That is, it can protect the prostate from enlargement when exposed to testosterone or any of its derivatives. Like, S4, it looks like it could be a great addition to any steroid complex to protect against prostate hyperplasia. In addition, RAD140 lowers lipid levels (LDL, HDL, Tryglicerides) without increasing liver enzymes.
Researches
RAD140 is an investigational selective androgen receptor modulator developed by Radius Health Inc for use in androgen replacement therapy. It was licensed by Ellipses Pharmaceuticals in 2020. Some of the potential benefits being investigated are for conditions such as muscle wasting and bone loss. Studies in rats have shown that RAD140 as a drug appears to be safer as a replacement therapy than testosterone. RAD140 also increased lean muscle mass in primates by acting on androgen receptors in skeletal tissue. The first human study was initiated in October 2017 and completed in September 2020 in postmenopausal women with breast cancer.
PEDs users opinion
There is a decent amount of unconfirmed information that can be cited due to its popularity in the bodybuilding community. The data itself is rather limited, as only a minority of people regularly record their blood tests and even fewer people get rigorously tested to determine exactly what effect YK11 has had on their bodies. Most YK11 users report impressive increases in muscle growth, strength gains, improved body composition while experiencing suppression if natural testosterone production. One of the more commonly reported side effects is scalp hair loss.
Effects
- Increases in muscle mass. RAD140 allows you to significantly increase muscle mass and give the body a more sculped look.
- Increase in strength indicators. Also, according to reddit users, RAD140 significantly increases strength indicators and their growth is more pronounced even than a set of muscle mass. Great for strength and martial arts athletes.
- Decreased body fat
Increased bone mineral density
Prostate protection. A feature and positive property of RAD140, like S4 is that it is a partial agonist of androgen receptors in prostate cells. So it binds to them without activating them, but blocking them from attaching DHT. Thus, there is no stimulation of prostate growth. In a sense, RAD140 protects the prostate from the androgenic effects of DHT when used in combination with DHT anabolic steroids. RAD140 is a potent androgen receptor agonist in breast cancer cells with a clear mechanism of action, including repression of the ESR1 gene.
Effect on the liver
Bro-science tells us that RAD140 is non-toxic to the liver. Anecdotal evidence and blood tests bone by bodybuilders also support this notion. We can conclude that in the majority of the population, RAD140 will not cause liver damage, but still to be absolutely sure- get a blood test before and after your cycle for liver enzymes ALT and AST. There is only one evidence of liver disease in a man who used RAD140 during a clinical trial, which has not yet been clearly explained.
Change in lipid profile
Although to a lesser extent than anabolic steroids, Aall SARMs can affect cholesterol levels to some extent. Most often, they decrease HDL (good cholesterol) levels and increase LDL (bad cholesterol). During your RAD140 cycle, you will need to take these blood tests to keep your cholesterol levels under control.
Testosterone suppression
RAD140 testosterone suppression usually occurs between the sixth and seventh week of your cycle, but only if your doses are in the 10 mg range. This may happen sooner if you are taking dosages such as 20 or 30 mg per day. To avoid this- do not take more than 10 mg per day during your RAD140 cycle.
Half-life
- 60 hours
Dosage
- Minimum working dosage (beginner) 5-10 mg
- Average dosage 10-20 mg
- Maximum recommended 30 mg
- Women 5-10 mg
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