DROLBAN XR (DROSTANOLONE ENANTHATE) (200 MG/ML)

Description

DESCRIPTION

Drolban XR (Drostanolone Enanthate)

Strength: 200 mg/ml
Active Ingredient: Drostanolone enanthate

DESCRIPTION

Drolban XR (Drostanolone Enanthate) 200 is a synthetic derivative of dihydrotestosterone, producing an
anabolic effect and promoting protein synthesis as well as creating positive nitrogen balance
in humans. Since it is a derivative of dihydrotestosterone, drostanolone does not aromatize
to estrogens. Drostanolone Enanthate 200 has significant anabolic and androgenic
properties promoting an increase in The strength and growth of muscle tissue while acting as
an estrogen antagonist. The combination of a short-acting propionate ester with a long acting enanthate ester pro- duces rapid increases in serum drostanolone levels with a
Sustained duration of 5-8 days.

CLINICAL PHARMACOLOGY

Anabolic steroids are synthetic derivatives of testosterone. Certain clinical effects and
adverse reactions demonstrate the androgenic properties of these drugs. Complete
dissociation of anabolic and androgenic effects has not been achieved. The actions of
anabolic steroids are thus similar to those of male sex hormones. Anabolic steroids suppress
the gonadotropic functions of the pituitary and may exert a direct effect upon the testes.
During exogenous administration of anabolic androgens, endogenous testosterone release
is inhibited through inhibition of pituitary luteinizing hormone (LH). At large doses,
spermatogenesis may be suppressed through feedback inhibition of pituitary
follicle-stimulating hormone (FSH). Drostanolone attaches to androgen receptors; increasing
nitrogen retention and protein synthesis. Drostanolone acts on DHT modulated pathways as
well, Drostanolone is a potent estrogen antagonist and does not aromatize to estrogen,
limiting expression of side effects often linked to estrogen such as water retention,
gynecomastia, and some types of high blood pressure. Drostanolone undergoes hepatic
metabolism with a half- life of 2-3 days after separation of the ester.

CONTRAINDICATIONS

Not indicated for women, children, or the elderly. Women who are pregnant or may become
pregnant because of possible masculinization of the fetus. Patients with nephrosis or the
nephrotic phase of nephritis. Patients with hypercalcemia. Patients suffering from testicular
cancer, prostate cancer, breast cancer, liver damage, kidney damage, stroke, high blood
pressure, heart disease or respiratory problems.

PRECAUTIONS

Elevated liver enzymes and in rare cases hepatic liver dysfunction may occur. Periodic liver
function should be monitored for changes including serum bilirubin, AST, ALT, and AP.
Edema may be increased in patients on concurrent adrenal cortical steroid or ACTH therapy.
Anabolic steroid hormones may increase low-density lipoproteins (LDL) and decrease high
density lipoproteins (HDL).Lipids levels generally return to normal upon discontinuation of
treatment. Anabolic steroids may reduce clotting factors II, V, VII, and X, and may increase
prothrombin time (PT). Patients should be instructed to report any use of warfarin and any
irregular bleeding.

DOSAGE AND ADMINISTRATION

Adult male: 100 – 150 mg injected IM every 3-5 days for a duration of 4-8 weeks.

STORAGE

Store in a cool dry place between 15 -25°C. Protect from light.

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